At the end of his life when faced with the succession issue he adopted Lucius Ceionius Commodus, but Lucius died of tuberculosis a year later. Now Hadrian executed a twin adoption. As Caesar he named Titus Aurelius Fulvus Boionius Arrius Antonius who would become Antonius Pius. He also required Antonius to adopt two young men to become his successors: Lucius Ceionius Commodus, son of the emperor designate who had died and Marcus Annius Verus grandson of a close friend of Hadrian.
Hadrian was very ill at the end of his life and had to be prevented from committing suicide on several occasions. He finally succumbed on July 10th, 138 A.D.