My high school physical science and physics teacher asked us one day in my freshman year in physical science class...
"What if everything we know, all reality, is really just the wet dream of some obese comatose woman in a hospital?"
We all looked around at each other with wide eyes but that concept stuck with me all these years.
haha I like that. A brain in a vat or deceived by a wicked demon would be more standard images for this idea, but that is certainly an image that sticks with you!